The Las Vegas Aces are on the road on Wednesday afternoon as they look to build on their league best record against the Phoenix Mercury.

The Mercury are in dead last in the WNBA this season, and they are without their three best players – Diana Taurasi, Brittney Griner and Skylar Diggins-Smith – in this game.

That's led to Las Vegas being heavily favored, and rightfully so, in this game.

Let's break down the odds and my best bet for this WNBA contest:

Aces vs. Mercury odds, spread and total

Aces vs. Mercury prediction and pick

This is a pretty easy bet for me, as we're looking at two complete opposite teams this season.

The Aces have a league best net rating of +19.7 this season while the Mercury (-10.6) are dead last in that statistic.

To make matters worse, the Mercury are down their three best players in this game.

This should be a blowout for the Aces, who have won 10 of 11 games and three straight. Las Vegas has blown out just about everyone this season – winning its last two games by 31 and 33 points.

If anyone can cover this spread, it's this Las Vegas team, and I have interest in betting on Phoenix with Griner and Taurasi out.

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Game odds refresh periodically and are subject to change.