The Indiana Fever are looking to snap a major losing streak on Friday night when they take on the Washington Mystics (No. 3 in the Eastern Conference).

Indiana is in last in the East and on a five-game skid, but it may be in luck on Friday with the Mystics – losers of two straight – potentially down four of their best players in this game.

Washington Mystics injury report

• Elena Delle Donne (ankle, questionable)
• Kristi Toliver (foot, out)
• Shakira Austin (hip, out)
• Natasha Cloud (ankle, questionable)

If Cloud and Delle Donne miss this game, the Mystics will be without three of their five players that average double-digit points per game on the season.

Oddsmakers seem to believe at least one will play, as Washington is still favored in this game.

Let's break down the odds and my favorite bet for this matchup:

Fever vs. Mystics odds, spread and total

Fever vs. Mystics prediction and pick

If there is one place to bet on the Fever, it is when they are on the road.

Aliyah Boston and company are an elite road team – at least at covering the spread – going 7-3-1 ATS this season.

That also lines up with the team's 4-7 straight up record on the road. With the Mystics banged up, this could be a spot where the Fever steal a game – especially if Delle Donne sits.

Washington locks up on defense (No. 1 in defensive rating), but the team is just eighth in the league in offensive rating.

That rating could plummet without one of its star scorers in this game, and the Fever – to their credit – have been a good offensive team this season (No. 4 in offensive rating).

I think there's a little value in hoping the injury report breaks in Indiana's favor, especially since the team has already impressed on the road in 2023.

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Game odds refresh periodically and are subject to change.